The ISL28633 is 5V zero-drift rail-to-rail input/output Programmable Gain Instrumentation Amplifiers (PGIA). These instrumentation amplifiers feature low offset, low noise, low gain error and high CMRR. They are ideal for high precision applications over the wide industrial temperature range. These instrumentation amplifiers are designed with a unique 2-bit, 3-state logic interface that allows up to 9 selectable gain settings. The ISL28533 single-ended output includes an additional uncommitted zero-drift amplifier, useful to buffer the REF input or used as a precision amplifier. The ISL28633 differential output amplifier includes a reference pin to set the common-mode output voltage to interface with differential input ADCs.